Clinical Research
Clinical and regulatory support, biobanking, and more are available to RI clinical researchers.
Clinical Research
Clinical and regulatory support, biobanking, and more are available to RI clinical researchers.
Brown University Health Clinical Research Center Services
Clinical and Regulatory Services
Located in the Brown University Health Coro complex in Providence, the Brown University Health CRC supports projects that require:
- Complete project management
- Tailored project support with participant recruitment, enrollment, data/specimen collection and or follow-up activities
- IRB initial submission and or regulatory study maintenance
For general questions about access to the center’s services and facilities, budget preparation and costs, and scheduling for initial meetings, please contact Evelyn Hipolito, manager, at 401-793-8788 or email EHipolito@Lifespan.org.
Visit the center's website to learn more.
Biobank Services
The LCRC Biobank supports biospecimens that:
- Require processing
- Have already been processed
- Are stored short-term and released
- Are stored long-term and released
- Are stored long-term with an unknown release date
- Are from the research community
- Are from a commercial source
Any biospecimens that are collected under a Lifespan IRB-approved protocol are eligible for storage in the biobank.
The biobank supports the following types of biospecimens:
- Plasma
- Serum
- Solid tissue (FFPE/slides)
- Whole blood
- Peripheral blood cells or bone marrow
- RBCs, PBMCs
- Saliva or buccal cells
- Urine
- Cerebral spinal fluid
- Cord blood
- Cord blood derivatives
- Other biological specimens
Lifespan and Brown have partnered to establish a Covid-19 biobank, housed at Rhode Island Hospital’s Clinical Research Center, to fuel research on this pandemic in our state.
The biobank includes the following samples:
- Plasma (0.5mLs)
- LI plasma (0.5mLs)
- Serum (0.5mLs)
- PBMCs (0.25mLs / ~2.5M cells)
Data available for each sample:
- Age
- Sex
- Race
- Health Insurance Status
- Social History
- Medical History
- Family COVID-19 History
- COVID-19 Symptoms Experience
- Clinical Actions Taken
Request Process
Investigators may request access to the specimens via the Lifespan/Brown Covid-19 Biobank Request Form.
A multi-institutional committee composed of representatives from Brown, The University of Rhode Island, Lifespan, Care New England, and the Providence VA Medical Center will review the requests on a rolling basis.
Eligibility & Regulatory Procedures
- Eligibility: All investigators at degree-granting institutions in Rhode Island are eligible to request access to Covid-19 biobank specimens.
- Regulatory Procedures and IRB requirements: For sample distribution, an IRB approval or exemption letter from your institution will be required.
If the researcher is not affiliated with Lifespan, data requests and sharing of specimens will require a Material Transfer Agreement (MTA) or Data Use Agreement (DUA), as applicable. Institutional Authorization Agreements (IAAs) must be established between non-Lifespan investigators’ home institutions and Lifespan.
Sample Retrieval
Investigators will pick up specimens by appointment only after receiving the appropriate approvals. Samples will be available for pick-up at CORO-West, One Hoppin Street, Suite 4.200. The researcher will be contacted with the time/date and is expected to bring all appropriate transport materials (packaging boxes, dry ice).
Fees & Citation Requirements
Lifespan will charge a cost per sample.
Rhode Island academic- and hospital-affiliated investigators:
- $75 - Serum & Plasma
- $125 - PBMC
Bio-pharma fees:
- $150/vial - Serum & Plasma
- $250/vial - PBMC
Investigators are required to cite Advance-CTR on any grants, publications, presentations and/or other products that result from access to the Covid-19 Biobank. Please contact AdvanceRI@brown.edu with any questions.
Clinical Trial Resources
Brown University Health Clinical Trials
Find a clinical trial at Brown University Health, or see a list of services on research groups, assets, and locations.
Clinical Studies Database
ClinicalTrials.gov is a service of the NIH National Library of Medicine. It is a searchable database of publicly and privately funded clinical studies conducted around the world.
- Set up a customized ClinicalTrials.gov RSS feed
- Learn about requirements for registering and reporting NIH-funded clinical trials
DIAMOND
DIAMOND (Development, Implementation, and AssessMent Of Novel Training in Domain-based competencies) is a NIH-funded, collaborative learning space for clinical research professionals and other members of research study teams. Training and assessment items included in the DIAMOND collection are searchable by competency domain and provide information and links to offerings for study teams. Resources and trainings are available in the following eight domains:
- Scientific concepts and research design
- Ethical and participant safety considerations
- Investigational products development and regulation
- Clinical study operations (GCPS)
- Study and site management
- Data management and informatics
- Leadership and professionalism
- Communication and teamwork
Clinical Research Units
CoresRI.org
Explore this directory of core research facilities, clinical research units, and services and instrumentation in Rhode Island. Users may search by instrument type, facility, category, institution or center and view a comprehensive list of resources available to them in the state.
Regulatory Contacts (IRB and IACUC)
Institution | Institutional Review Board (IRB) | Institutional Animal Care and Use Committee (IACUC) |
---|---|---|
Brown University |
Sheila Vandal
Vanessa Sherman
|
N/A |
Butler Hospital |
Cheryl Cordeiro
|
N/A |
Kent Hospital |
Donna Coppola
Dorinda Williams
|
N/A |
Lifespan |
Candy Frater
|
Jacqueline Poore
|
Providence College |
Mary Harmon-Vukic
|
N/A |
Rhode Island College | Emily Cook
IRB Chair ecook@ric.edu |
N/A |
University of Rhode Island |
Mary Riedford
|
N/A |
VA Providence Healthcare System |
Val Micucci
|
N/A |
Women and Infants Hospital |
Amber Latronica
|
N/A |