Advance-CTR

Clinical Research

Clinical and regulatory support, biobanking, and more are available to RI clinical researchers.

Brown University Health Clinical Research Center Services

Clinical and Regulatory Services

Located in the Brown University Health Coro complex in Providence, the Brown University Health CRC supports projects that require:

  • Complete project management
  • Tailored project support with participant recruitment, enrollment, data/specimen collection and or follow-up activities
  • IRB initial submission and or regulatory study maintenance

For general questions about access to the center’s services and facilities, budget preparation and costs, and scheduling for initial meetings, please contact Evelyn Hipolito, manager, at 401-793-8788 or email EHipolito@Lifespan.org

Visit the center's website to learn more.

Biobank Services

The LCRC Biobank supports biospecimens that:
  • Require processing
  • ​Have already been processed
  • Are stored short-term and released
  • Are stored long-term and released
  • Are stored long-term with an unknown release date
  • Are from the research community
  • ​​Are from a commercial source

Any biospecimens that are collected under a Brown University Health IRB-approved protocol are eligible for storage in the biobank.

The biobank supports the following types of biospecimens:
  • Plasma
  • Serum
  • Solid tissue (FFPE/slides)
  • Whole blood
  • Peripheral blood cells or bone marrow​
  • RBCs, PBMCs
  • Saliva or buccal cells
  • Urine
  • Cerebral spinal fluid
  • Cord blood
  • Cord blood derivatives
  • Other biological specimens

Request Biobank Access

Lifespan and Brown have partnered to establish a Covid-19 biobank, housed at Rhode Island Hospital’s Clinical Research Center, to fuel research on this pandemic in our state.

The biobank includes the following samples:
  • Plasma (0.5mLs)
  • LI plasma (0.5mLs) 
  • Serum (0.5mLs)
  • PBMCs (0.25mLs / ~2.5M cells)
Data available for each sample: 
  • Age
  • Sex
  • Race
  • Health Insurance Status
  • Social History
  • Medical History
  • Family COVID-19 History
  • COVID-19 Symptoms Experience
  • Clinical Actions Taken

Request Process

Investigators may request access to the specimens via the Lifespan/Brown Covid-19 Biobank Request Form

A multi-institutional committee composed of representatives from Brown, The University of Rhode Island, Lifespan, Care New England, and the Providence VA Medical Center will review the requests on a rolling basis.

Eligibility & Regulatory Procedures

  • Eligibility: All investigators at degree-granting institutions in Rhode Island are eligible to request access to Covid-19 biobank specimens.
  • Regulatory Procedures and IRB requirements: For sample distribution, an IRB approval or exemption letter from your institution will be required.

If the researcher is not affiliated with Lifespan, data requests and sharing of specimens will require a Material Transfer Agreement (MTA) or Data Use Agreement (DUA), as applicable. Institutional Authorization Agreements (IAAs) must be established between non-Lifespan investigators’ home institutions and Lifespan.

Sample Retrieval

Investigators will pick up specimens by appointment only after receiving the appropriate approvals. Samples will be available for pick-up at CORO-West, One Hoppin Street, Suite 4.200. The researcher will be contacted with the time/date and is expected to bring all appropriate transport materials (packaging boxes, dry ice).

Fees & Citation Requirements

Lifespan will charge a cost per sample. 

Rhode Island academic- and hospital-affiliated investigators: 
  • $75 - Serum & Plasma
  • $125 - PBMC
Bio-pharma fees: 
  • $150/vial - Serum & Plasma
  • $250/vial - PBMC​

Investigators are required to cite Advance-CTR on any grants, publications, presentations and/or other products that result from access to the Covid-19 Biobank. Please contact AdvanceRI@brown.edu with any questions. 

Request COVID-19 Biobank Access

Clinical Trial Resources

Brown University Health Clinical Trials

Find a clinical trial at Brown University Health, or see a list of services on research groups, assets, and locations. 

Clinical Studies Database

ClinicalTrials.gov is a service of the NIH National Library of Medicine. It is a searchable database of publicly and privately funded clinical studies conducted around the world.

DIAMOND

DIAMOND (Development, Implementation, and AssessMent Of Novel Training in Domain-based competencies) is a NIH-funded, collaborative learning space for clinical research professionals and other members of research study teams. Training and assessment items included in the DIAMOND collection are searchable by competency domain and provide information and links to offerings for study teams. Resources and trainings are available in the following eight domains: 

  1. Scientific concepts and research design
  2. Ethical and participant safety considerations 
  3. Investigational products development and regulation 
  4. Clinical study operations (GCPS)
  5. Study and site management
  6. Data management and informatics
  7. Leadership and professionalism 
  8. Communication and teamwork 

Explore the DIAMOND portal

Clinical Research Units

CoresRI.org

Explore this directory of core research facilities, clinical research units, and services and instrumentation in Rhode Island. Users may search by instrument type, facility, category, institution or center and view a comprehensive list of resources available to them in the state.

Regulatory Contacts (IRB and IACUC)

InstitutionInstitutional Review Board (IRB)Institutional Animal Care and Use Committee (IACUC)
Brown University

Sheila Vandal 
IRB Manager 
sheila_vandal@brown.edu

Vanessa Sherman 
IRB Specialist 
vanessa_sherman@brown.edu

N/A
Butler Hospital Cheryl Cordeiro 
IRB Coordinator 
CCordeiro@butler.org
N/A
Kent Hospital

Donna Coppola 
IRB Coordinator 
DMCoppola@carene.org

Dorinda Williams 
IRB Coordinator 
dorwilliams@carene.org

N/A
Brown University HealthCandy Frater 
IRB Manager 
sfrater@lifespan.org
Jacqueline Poore 
Research Compliance Program Senior Administrator 
JPoore@lifespan.org
Providence CollegeMary Harmon-Vukic 
IRB Chair 
mharmon@providence.edu
N/A
Rhode Island CollegeEmily Cook 
IRB Chair 
ecook@ric.edu
N/A
University of Rhode Island Mary Riedford 
Research Integrity Assistant Director 
mcriedford@uri.edu
N/A
VA Providence Healthcare SystemVal Micucci 
IRB Coordinator 
val.micucci@va.gov
N/A
Women and Infants HospitalAmber Latronica 
Research Systems & Compliance Specialist 
alatronica@wihri.org
N/A