Data Management & Analysis

Explore these data management tools and resources for REDCap, computation and visualization, the N3C Data Enclave, and more.

COVID-19 clinical data is available for research through the new N3C analytics platform.

Data from more than 1.6M COVID+ cases are now available to Rhode Island researchers through the new National COVID Cohort Collaborative (N3C) data platform.

In addition to the vast amounts of data available for coronavirus research, the N3C also aims to help scientists analyze these data to understand the disease and develop treatments. The N3C Data Enclave was officially launched in September 2020 and is funded by the National Center for Advancing Translational Sciences (NCATS).

Advance-CTR has joined a national IDeA-CTR effort, led by West Virginia CTSI, to contribute RI data to the platform. This work is currently underway. 

What's Available 

The N3C enclave currently holds data related to roughly:

  • 56 sites
  • 5.9 million persons
  • 1.6 million COVID+ cases
  • 326 million procedures 
  • 582.8M million clinical observations
  • 3.1 billion lab results
  • ...and more!

The N3C aims to aggregate, harmonize, and make accessible vast amounts of data from healthcare providers nationwide to accelerate advances in COVID-19 research and clinical care. With the uncertainty of the COVID-19 global pandemic, the scientific community and Clinical and Translational Science Awards (CTSA) Program created the N3C partnership to overcome technical, regulatory, policy, and governance barriers to harmonizing and sharing individual-level clinical data.

Register for Access

Your institution must have executed a Data Use Agreement prior to registering (in process or completed for Advance-CTR partner sites). Please use your institutional email address when registering. After you register for an account, access is granted within 48 business hours.

Three levels of data are available:

  1. Synthetic data or a safe data derivative,
  2. De-identified data; and
  3. Limited data.

If you request limited data, you will need IRB approval from your home institution and must provide documentation of human subject research protection training. If you have questions, follow the drop-down menu to the Support Desk page.

Data Use Requests

A Data Use Request (DUR) is an online application submitted by the researcher within the N3C Data Enclave that describes the scope and nature of the project and justifies the requested data access tier. Approval of the DUR by the Data Access Committee (DAC) is required before a researcher can access data within the enclave. (Approved DURs are valid for 1 year.) Please contact Advance-CTR for important information on this process at .

Clinical Domain Teams

Domain teams are multidisciplinary research teams focusing on specific aspects of COVID-19 ranging from diabetes to pediatrics. These teams collaboratively submit data access requests to avoid duplication of efforts and to ensure appropriate expertise while answering questions about the pandemic.  See the list of clinical domain teams.

Additional Benefits

  • Generating sample data for pilot projects and grant proposals
  • Training algorithms on a very large cohort of patients
  • Opportunities to train junior researchers (the domain teams can offer support and a network for these investigators)
  • Informatics and statistics opportunities for innovation and evaluation
  • Opportunities for clinicians to investigate COVID-19 treatment patterns and disease progression

More Information

Advance-CTR is testing a statewide REDCap instance that will soon be available to all RI investigators regardless of institutional affiliation. Subscribe to our weekly email newsletter to receive the latest updates.

What Is REDCap?

REDCap is a secure web application that serves as an electronic data capture tool for research studies. REDCap allows users to build and manage online surveys and databases quickly and easily. 

REDCap Resources

Explore Reference Materials 

Watch Online Tutorials

Catch up on workshops and tutorials from our Biostatistics Core on our YouTube page. Topics include our advanced users workshop on randomization, longitudinal survey studies, and more. 

Watch Now

Sign Up for REDCap Workshops

The Advance-CTR Biostatistics Core offers complimentary workshops to novice and advanced REDCap users on a variety of topic areas. 

Sign Up Now

Brown University librarians offer a coordinated suite of services and workshops to support the research lifecycle, from planning and conducting, to publication. Assistance includes:

  • Conducting a Literature Review
  • Organizing Citations 
  • Complying with Funders’ Public Access Policies
  • Obtaining and using an Open Researcher and Contributor ID (ORCID)
  • Measuring Impact 

The Library also makes available Frequently Asked Questions for the NIH Public Access Policy

Sign up for tutorials offered by the Brown library on a variety of subjects including: Finding open access articles, depositing a manuscript for NIH and NSF public access compliance, writing a data management and sharing plan, and more. 

Related Resources: 

The Center for Computation and Visualization provides high-performance computing and visualization services to the Brown community. CCV also collaborates with researchers on projects across a vast range of disciplines.

Explore CCV: 

  • Stronghold
  • Oscar
  • User Manuals
  • Data Science
  • CCV Status

Go to CCV

New to clinical and translational research? Explore these training modules from the DaCCoTA CTR program.

Modules include: 

  • Running the Statistical Gauntlet in R
  • Power Analysis in R
  • Exploratory Data Analysis 
  • Introduction to Data Analysis in SPSS

Explore the Portal